Database


Enediyne Genome Neighborhood Network (GNN)

A virtual survey of the GenBank and JGI Genome databases revealed 87 enediyne biosynthetic gene clusters from 78 bacteria strains in a genome neighborhood network.

A virtual survey of the GenBank and JGI Genome databases revealed 87 enediyne biosynthetic gene clusters from 78 bacteria strains. An enediyne genome neighborhood network (GNN) was constructed to analyze these gene clusters in a high-throughput manner. Please reference J. D. Rudolf, X. Yan, and B. Shen. (2016J. Ind. Microbiol. Biotechnol. 43, 261-276.


P450s in Streptomyces (SSN)

 A sequence similarity network (SSN) of the current catalytic landscape of P450s within the Streptomyces genus.

We surveyed the current catalytic landscape of P450s within the Streptomyces genus. A sequence similarity network (SSN) was constructed to analyze sequence–function relationships of these remarkable biocatalysts. Please reference J. D. Rudolf, C.-Y. Chang, M. Ma, and B. Shen. (2017Nat. Prod. Rep., in press.